Postdoctoral position on a project funded by ERC is opened
Location: BIOCEV, Charles University, Vestec, Czech Republic
Employer: Charles University, Prague, Czech Republic
The position is part of a larger project funded by ERC. The project is focused on the investigation of oxymonads - eukaryotes without mitochondria (Karnkowska et al., Curr Biol 2016). Major aims are to disclose their metabolism, particularly FeS cluster synthesis, and to develop tool for their study (axenic cultivation, transfection, RNAi, CRISPR/Cas9). Furthermore, we will examine other potential amitochondriates (Pelomyxa, Retortamonas) and test the possibilities of mitochondrial knock-outs in selected anaerobes with very simple mitochondria (Entamoeba, Giardia).
The work on the project will be carried out in the new institute BIOCEV in the laboratory of Vladimir Hampl. Qualification in cell biology (cell fractionation, immunofluorescence, genetic transformation, RNAi, immunolocalisation, immunoprecipitation, two-hybrid systems), cultivation techniques or genomics (single cell isolation, NGS library preparations, data assembly, genome annotation, methods of comparative genomics) is advantage but enthusiasm and invention are necessary conditions. For more information and more precise job descriptions please contact Vladimir Hampl.